Papers
2024
Reshetnyak, Yana K., Oleg A. Andreev, and Donald M. Engelman. “Aiming the Magic Bullet: Targeted Delivery of Imaging and Therapeutic Agents to Solid Tumors by pHLIP Peptides.” Frontiers in Pharmacology 15 (2023): 1355893. Link
DuPont M, Klumpp C, Iraca M, Allababidi D, Visca H, Engelman DM, Andreev OA, Moshnikova A, Reshetnyak YK. pHLIP targeted intracellular delivery of calicheamicin. Int J Pharm. 2024 Feb 28;654:123954. doi: 10.1016/j.ijpharm.2024.123954. Epub ahead of print. PMID: 38428548. PubMed
2023
Matsui, Toma, Yuki Toda, Haruka Sato, Rina Itagaki, Kazuya Konishi, Anna Moshnikova, Oleg A. Andreev, Shigekuni Hosogi, Yana K. Reshetnyak, and Eishi Ashihara. “Targeting acidic pre-metastatic niche in lungs by pH Low Insertion Peptide and its utility for anti-metastatic therapy.” Frontiers in Oncology 13: 1258442.
Silva TFD, Visca H, Klumpp C, Andreev OA, Reshetnyak YK, Machuqueiro M. Arginine Residues Modulate the Membrane Interactions of pHLIP Peptides. J Chem Inf Model. 2023, In press, PubMed
Ye Q, Jo J, Wang CY, Oh H, Choy TJ, Kim K, Dâ Alessandro A, Reshetnyak YK, Jung SY, Chen Z, Marrelli SP, Lee HK. Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a NO-CCL2-CCR2 pathway. bioRxiv [Preprint]. 2023. PubMed
DuPont M, Visca H, Moshnikova A, Engelman DM, Reshetnyak YK, Andreev OA. Tumor Treatment by pHLIP-Targeted Antigen Delivery. Front. Bioeng. Biotechnol. 2023, 10, 1082290. PubMed
2022
Moshnikova A, DuPont M, Visca H, Engelman DM, Andreev OA, Reshetnyak YK. Eradication of tumors and development of anti-cancer immunity using STINGa targeted by pHLIP. Front Oncol. 2022, 12, 1023959. PubMed
Moshnikova A, Golijanin B, Amin A, Doyle J, Kott O, Gershman B, DuPont M, Li Y, Lu X, Engelman DM, Andreev OA, Reshetnyak YK and Golijanin D (2022) Targeting bladder urothelial carcinoma with pHLIP-ICG and inhibition of urothelial cancer cell proliferation by pHLIP-amanitin. Front. Urol., 2022, 2, 868919. PubMed
Visca H, DuPont M, Moshnikova A, Crawford T, Engelman DM, Andreev OA, Reshetnyak YK. pHLIP Peptides Target Acidity in Activated Macrophages. Mol Imaging Biol. 2022, In press. PubMed
Bauer D, Visca H, Weerakkody A, Carter LM, Samuels Z, Kaminsky S, Andreev OA, Reshetnyak YK, Lewis JS. PET Imaging of Acidic Tumor Environment With 89Zr-labeled pHLIP Probes. Front Oncol. 2022 May 19;12:882541. PubMed
Zhang X, Rotllan N, Canfrán-Duque A, Sun J, Toczek J, Moshnikova A, Malik S, Price NL, Araldi E, Zhong W, Sadeghi MM, Andreev OA, Bahal R, Reshetnyak YK, Suárez Y, Fernández-Hernando C. Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression. Circ Res. 2022 May 9:101161CIRCRESAHA121320296. PubMed
Hulikova A, Park KC, Loonat AA, Gunadasa-Rohling M, Curtis MK, Chung YJ, Wilson A, Carr CA, Trafford AW, Fournier M, Moshnikova A, Andreev OA, Reshetnyak YK, Riley PR, Smart N, Milne TA, Crump NT, Swietach P. Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart. Basic Res Cardiol. 2022 Mar 31;117(1):17. PubMed
2021
Miska J, Rashidi A, Lee-Chang C, Gao P, Lopez-Rosas A, Zhang P, Burga R, Castro B, Xiao T, Han Y, Hou D, Sampat S, Cordero A, Stoolman JS, Horbinski CM, Burns M, Reshetnyak YK, Chandel NS, Lesniak MS. Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma. Sci Adv. 2021 Feb 17;7(8):eabc8929. PubMed
Gayle S, Aiello R, Leelatian N, Beckta JM, Bechtold J, Bourassa P, Csengery J, Maguire RJ, Marshall D, Sundaram RK, Van Doorn J, Jones K, Moore H, Lopresti-Morrow L, Paradis T, Tylaska L, Zhang Q, Visca H, Reshetnyak YK, Andreev OA, Engelman DM, Glazer PM, Bindra RS, Paralkar VM. Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity. NAR Cancer. 2021 Jun 4;3(2):zcab021. PubMed
Wilson AD, Richards MA, Curtis MK, Rohling M, Monterisi S, Loonat AA, Miller J, Ball V, Lewis A, Tyler D, Moshnikova A, Andreev OA, Reshetnyak YK, Carr C, Swietach P. Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH. Cardiovasc Res. 2021 Dec 13:cvab364. PubMed
2020
Wu H, Estrella V, Beatty M, Abrahams D, El-Kenawi A, Russell S, Ibrahim-Hashim A, Longo DL, Reshetnyak YK, Moshnikova A, Andreev OA, Luddy K, Damaghi M, Kodumudi K, Pillai SR, Enriquez-Navas P, Pilon-Thomas S, Swietach P, Gillies RJ. T-cells produce acidic niches in lymph nodes to suppress their own effector functions. Nat Commun. 2020 Aug 17;11(1):4113. PubMed
Crawford T, Moshnikova A, Roles S, Weerakkody D, DuPont M, Carter LM, Shen J, Engelman DM, Lewis JS, Andreev OA, Reshetnyak YK. pHLIP ICG for delineation of tumors and blood flow during fluorescence-guided surgery. Sci Rep. 2020 Oct 27;10(1):18356. PubMed
Slaybaugh G, Weerakkody D, Engelman DM, Andreev OA, Reshetnyak YK. Kinetics of pHLIP peptide insertion into and exit from a membrane. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12095-12100. PubMed
Henry KE, Chaney AM, Nagle VL, Cropper HC, Mozaffari S, Slaybaugh G, Parang K, Andreev OA, Reshetnyak YK, James ML, Lewis JS. Demarcation of Sepsis-Induced Peripheral and Central Acidosis with pH (Low) Insertion Cycle Peptide. J Nucl Med. 2020 Sep;61(9):1361-1368. PubMed
Reshetnyak YK, Moshnikova A, Andreev OA, Engelman DM. Targeting Acidic Diseased Tissues by pH-Triggered Membrane-Associated Peptide Folding. Front Bioeng Biotechnol. 2020 Apr 28;8:335. PubMed
Brito J, Golijanin B, Kott O, Moshnikova A, Mueller-Leonhard C, Gershman B, Andreev OA, Reshetnyak YK, Amin A, Golijanin D. Ex-vivo Imaging of Upper Tract Urothelial Carcinoma Using Novel pH Low Insertion Peptide (Variant 3), a Molecular Imaging Probe. Urology. 2020 May;139:134-140. PubMed
2019
Sahraei M, Chaube B, Liu Y, Sun J, Kaplan A, Price NL, Ding W, Oyaghire S, García-Milian R, Mehta S, Reshetnyak YK, Bahal R, Fiorina P, Glazer PM, Rimm DL, Fernández-Hernando C, Suárez Y. Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response. J Clin Invest. 2019 Dec 2;129(12):5518-5536. PubMed
Price NL, Miguel V, Ding W, Singh AK, Malik S, Rotllan N, Moshnikova A, Toczek J, Zeiss C, Sadeghi MM, Arias N, Baldán Á, Andreev OA, Rodríguez-Puyol D, Bahal R, Reshetnyak YK, Suárez Y, Fernández-Hernando C, Lamas S. Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis. JCI Insight. 2019 Nov 14;4(22):e131102. PubMed
Roberts S, Strome A, Choi C, Andreou C, Kossatz S, Brand C, Williams T, Bradbury M, Kircher MF, Reshetnyak YK, Grimm J, Lewis JS, Reiner T. Acid specific dark quencher QC1 pHLIP for multi-spectral optoacoustic diagnoses of breast cancer. Sci Rep. 2019 Jun 12;9(1):8550. PubMed
Wei D, Engelman DM, Reshetnyak YK, Andreev OA. Mapping pH at Cancer Cell Surfaces. Mol Imaging Biol. 2019 Dec;21(6):1020-1025. PubMed
2018
Rinaldi F, Hanieh PN, Del Favero E, Rondelli V, Brocca P, Pereira MC, Andreev OA, Reshetnyak YK, Marianecci C, Carafa M. Decoration of Nanovesicles with pH (Low) Insertion Peptide (pHLIP) for Targeted Delivery. Nanoscale Res Lett. 2018 Dec 4;13(1):391. PubMed
Karabadzhak AG, Weerakkody D, Deacon J, Andreev OA, Reshetnyak YK, Engelman DM. Bilayer Thickness and Curvature Influence Binding and Insertion of a pHLIP Peptide. Biophys J. 2018 May 8;114(9):2107-2115. PubMed
Vila-Viçosa D, Silva TFD, Slaybaugh G, Reshetnyak YK, Andreev OA, Machuqueiro M. Membrane-Induced p Ka Shifts in wt-pHLIP and Its L16H Variant. J Chem Theory Comput. 2018 Jun 12;14(6):3289-3297. PubMed
Wyatt LC, Moshnikova A, Crawford T, Engelman DM, Andreev OA, Reshetnyak YK. Peptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumors. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2811-E2818. PubMed
2017
Daniels JL, Crawford TM, Andreev OA, Reshetnyak YK. Synthesis and characterization of pHLIP® coated gold nanoparticles. Biochem Biophys Rep. 2017 Feb 28;10:62-69. PubMed
Wyatt LC, Lewis JS, Andreev OA, Reshetnyak YK, Engelman DM. Applications of pHLIP Technology for Cancer Imaging and Therapy: (Trends in Biotechnology 35, 653-664, 2017). Trends Biotechnol. 2018 Dec;36(12):1300. PubMed
2016
Narayanan T, Weerakkody D, Karabadzhak AG, Anderson M, Andreev OA, Reshetnyak YK. pHLIP Peptide Interaction with a Membrane Monitored by SAXS. J Phys Chem B. 2016 Nov 10;120(44):11484-11491. PubMed
Pereira MC, Pianella M, Wei D, Moshnikova A, Marianecci C, Carafa M, Andreev OA, Reshetnyak YK. pH-sensitive pHLIP® coated niosomes. Mol Membr Biol. 2016 May-Aug;33(3-5):51-63. PubMed
Weerakkody D, Andreev OA, Reshetnyak YK. Insertion into lipid bilayer of truncated pHLIP® peptide. Biochem Biophys Rep. 2016 Dec;8:290-295. PubMed
Golijanin J, Amin A, Moshnikova A, Brito JM, Tran TY, Adochite RC, Andreev GO, Crawford T, Engelman DM, Andreev OA, Reshetnyak YK, Golijanin D. Targeted imaging of urothelium carcinoma in human bladders by an ICG pHLIP peptide ex vivo. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11829-11834. PubMed
Weerakkody D, Moshnikova A, El-Sayed NS, Adochite RC, Slaybaugh G, Golijanin J, Tiwari RK, Andreev OA, Parang K, Reshetnyak YK. Novel pH-Sensitive Cyclic Peptides. Sci Rep. 2016 Aug 12;6:31322. PubMed
1: Demoin DW, Wyatt LC, Edwards KJ, Abdel-Atti D, Sarparanta M, Pourat J, Longo VA, Carlin SD, Engelman DM, Andreev OA, Reshetnyak YK, Viola-Villegas N, Lewis JS. PET Imaging of Extracellular pH in Tumors with (64)Cu- and (18)F-Labeled pHLIP Peptides: A Structure-Activity Optimization Study. Bioconjug Chem. 2016 Sep 21;27(9):2014-23. PubMed
Anderson M, Moshnikova A, Engelman DM, Reshetnyak YK, Andreev OA. Probe for the measurement of cell surface pH in vivo and ex vivo. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8177-81. Pubmed
Shrestha S, Cooper LN, Andreev OA, Reshetnyak YK, Antosh MP. Gold Nanoparticles for Radiation Enhancement in Vivo. Jacobs J Radiat Oncol. 2016 Apr;3(1):026. Pubmed
Adochite RC, Moshnikova A, Golijanin J, Andreev OA, Katenka NV, Reshetnyak YK. Comparative Study of Tumor Targeting and Biodistribution of pH (Low) Insertion Peptides (pHLIP® Peptides) Conjugated with Different Fluorescent Dyes. Mol Imaging Biol. 2016 Oct;18(5):686-96. PubMed
2015
Tapmeier TT, Moshnikova A, Beech J, Allen D, Kinchesh P, Smart S, Harris A, McIntyre A, Engelman DM, Andreev OA, Reshetnyak YK, Muschel RJ. The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9710-5. PubMed
Reshetnyak YK. Imaging Tumor Acidity: pH-Low Insertion Peptide Probe for Optoacoustic Tomography. Clin Cancer Res. 2015 Oct 15;21(20):4502-4. PubMed
Sharma GP, Reshetnyak YK, Andreev OA, Karbach M, Müller G. Coil-helix transition of polypeptide at water-lipid interface. J Stat Mech. 2015 Jan, P01034. PubMed
Pereira MC, Reshetnyak YK, Andreev OA. Advanced targeted nanomedicine. J Biotechnol. 2015 May 20;202:88-97. PubMed
Antosh MP, Wijesinghe DD, Shrestha S, Lanou R, Huang YH, Hasselbacher T, Fox D, Neretti N, Sun S, Katenka N, Cooper LN, Andreev OA, Reshetnyak YK. Enhancement of radiation effect on cancer cells by gold-pHLIP. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5372-6. PubMed
2014
Karabadzhak AG, An M, Yao L, Langenbacher R, Moshnikova A, Adochite RC, Andreev OA, Reshetnyak YK, Engelman DM. pHLIP-FIRE, a cell insertion-triggered fluorescent probe for imaging tumors demonstrates targeted cargo delivery in vivo. ACS Chem Biol. 2014 Nov 21;9(11):2545-53. PubMed
Adochite RC, Moshnikova A, Carlin SD, Guerrieri RA, Andreev OA, Lewis JS, Reshetnyak YK. Targeting breast tumors with pH (low) insertion peptides. Mol Pharm. 2014 Aug 4;11(8):2896-905. PubMed
Andreev OA, Engelman DM, Reshetnyak YK. Targeting diseased tissues by pHLIP insertion at low cell surface pH. Front Physiol. 2014 Mar 13;5:97. PubMed
Cruz-Monserrate Z, Roland CL, Deng D, Arumugam T, Moshnikova A, Andreev OA, Reshetnyak YK, Logsdon CD. Targeting pancreatic ductal adenocarcinoma acidic microenvironment. Sci Rep. 2014 Mar 19;4:4410. PubMed
Viola-Villegas NT, Carlin SD, Ackerstaff E, Sevak KK, Divilov V, Serganova I, Kruchevsky N, Anderson M, Blasberg RG, Andreev OA, Engelman DM, Koutcher JA, Reshetnyak YK, Lewis JS. Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7254-9. PubMed
2013
Weerakkody D, Moshnikova A, Thakur MS, Moshnikova V, Daniels J, Engelman DM, Andreev OA, Reshetnyak YK. Family of pH (low) insertion peptides for tumor targeting. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5834-9. PubMed
Yao L, Daniels J, Wijesinghe D, Andreev OA, Reshetnyak YK. pHLIP®-mediated delivery of PEGylated liposomes to cancer cells. J Control Release. 2013 May 10;167(3):228-37. PubMed
Moshnikova A, Moshnikova V, Andreev OA, Reshetnyak YK. Antiproliferative effect of pHLIP-amanitin. Biochemistry. 2013 Feb 19;52(7):1171-8. PubMed
Sosunov EA, Anyukhovsky EP, Sosunov AA, Moshnikova A, Wijesinghe D, Engelman DM, Reshetnyak YK, Andreev OA. pH (low) insertion peptide (pHLIP) targets ischemic myocardium. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):82-6. PubMed
Yao L, Daniels J, Moshnikova A, Kuznetsov S, Ahmed A, Engelman DM, Reshetnyak YK, Andreev OA. pHLIP peptide targets nanogold particles to tumors. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):465-70. PubMed
Wijesinghe D, Arachchige MC, Lu A, Reshetnyak YK, Andreev OA. pH dependent transfer of nano-pores into membrane of cancer cells to induce apoptosis. Sci Rep. 2013 Dec 20;3:3560. PubMed
2012
Reshetnyak YK, Prudence CN, Segala J, Markin VS, Andreev OA. Parking problem and negative cooperativity of binding of myosin subfragment 1 to F-actin. Biochem Biophys Res Commun. 2012 Sep 7;425(4):746-9. PubMed
Daumar P, Wanger-Baumann CA, Pillarsetty N, Fabrizio L, Carlin SD, Andreev OA, Reshetnyak YK, Lewis JS. Efficient (18)F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation. Bioconjug Chem. 2012 Aug 15;23(8):1557-66. PubMed
Karabadzhak AG, Weerakkody D, Wijesinghe D, Thakur MS, Engelman DM, Andreev OA, Markin VS, Reshetnyak YK. Modulation of the pHLIP transmembrane helix insertion pathway. Biophys J. 2012 Apr 18;102(8):1846-55. PubMed
Macholl S, Morrison MS, Iveson P, Arbo BE, Andreev OA, Reshetnyak YK, Engelman DM, Johannesen E. In vivo pH imaging with (99m)Tc-pHLIP. Mol Imaging Biol. 2012 Dec;14(6):725-34. PubMed
2011
Barrera FN, Weerakkody D, Anderson M, Andreev OA, Reshetnyak YK, Engelman DM. Roles of carboxyl groups in the transmembrane insertion of peptides. J Mol Biol. 2011 Oct 21;413(2):359-71. PubMed
Reshetnyak YK, Yao L, Zheng S, Kuznetsov S, Engelman DM, Andreev OA. Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP. Mol Imaging Biol. 2011 Dec;13(6):1146-56. PubMed
Wijesinghe D, Engelman DM, Andreev OA, Reshetnyak YK. Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide. Biochemistry. 2011 Nov 29;50(47):10215-22. PubMed
2010
An M, Wijesinghe D, Andreev OA, Reshetnyak YK, Engelman DM. pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20246-50. PubMed
Andreev OA, Karabadzhak AG, Weerakkody D, Andreev GO, Engelman DM, Reshetnyak YK. pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4081-6. PubMed
Andreev OA, Engelman DM, Reshetnyak YK. pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents. Mol Membr Biol. 2010 Oct;27(7):341-52. PubMed
Musial-Siwek M, Karabadzhak A, Andreev OA, Reshetnyak YK, Engelman DM. Tuning the insertion properties of pHLIP. Biochim Biophys Acta. 2010 Jun;1798(6):1041-6. PubMed
Yao L, Segala J, Bucci AJ, Andreev GO, Reshetnyak YK, Andreev OA. Fluorescence anistropy imaging microscopy. Microscopy: Science, Technology, Applications and Education, Formatex Research Center, 2010, 3:2072-8. ResearchGate
2009
Andreev OA, Engelman DM, Reshetnyak YK. Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP). Chim Oggi. 2009 Mar 1;27(2):34-37. PubMed
Hixon J, Reshetnyak YK. Algorithm for the Analysis of Tryptophan Fluorescence Spectra and Their Correlation with Protein Structural Parameters. Algorithms 2009, vol. 2: 1155-76. Journal
Segala J, Engelman DM, Reshetnyak YK, Andreev OA. Accurate analysis of tumor margins using a fluorescent pH Low Insertion Peptide (pHLIP). Int J Mol Sci. 2009 Aug 4;10(8):3478-87. PubMed
Vāvere AL, Biddlecombe GB, Spees WM, Garbow JR, Wijesinghe D, Andreev OA, Engelman DM, Reshetnyak YK, Lewis JS. A novel technology for the imaging of acidic prostate tumors by positron emission tomography. Cancer Res. 2009 May 15;69(10):4510-6. PubMed
Yao L, Andreev GO, Reshetnyak YK, Andreev OA. Fabrication of semiconductor nanowires by conjugation of quantum dots to actin filaments. Anal Bioanal Chem. 2009 Nov;395(5):1563-6. PubMed
2008
Jain N, Reshetnyak YK, Gao L, Chiarelli MP, Cho BP. Fluorescence probing of aminofluorene-induced conformational heterogeneity in DNA duplexes. Chem Res Toxicol. 2008 Feb;21(2):445-52. PubMed
Reshetnyak YK, Andreev OA, Segala M, Markin VS, Engelman DM. Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15340-5. PubMed
Shen C, Menon R, Das D, Bansal N, Nahar N, Guduru N, Jaegle S, Peckham J, Reshetnyak YK. The protein fluorescence and structural toolkit: Database and programs for the analysis of protein fluorescence and structural data. Proteins. 2008 Jun;71(4):1744-54. PubMed
Zoonens M, Reshetnyak YK, Engelman DM. Bilayer interactions of pHLIP, a peptide that can deliver drugs and target tumors. Biophys J. 2008 Jul;95(1):225-35. PubMed
2007
Andreev OA, Dupuy AD, Segala M, Sandugu S, Serra DA, Chichester CO, Engelman DM, Reshetnyak YK. Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7893-8. PubMed
Andreev OA, Reshetnyak YK. Mechanism of formation of actomyosin interface. J Mol Biol. 2007 Jan 19;365(3):551-4. PubMed
Reshetnyak YK, Segala M, Andreev OA, Engelman DM. A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers. Biophys J. 2007 Oct 1;93(7):2363-72. PubMed
Torrent M, Cuyás E, Carreras E, Navarro S, López O, de la Maza A, Nogués MV, Reshetnyak YK, Boix E. Topography studies on the membrane interaction mechanism of the eosinophil cationic protein. Biochemistry. 2007 Jan 23;46(3):720-33. PubMed
2006
Reshetnyak YK, Andreev OA, Lehnert U, Engelman DM. Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6460-5. PubMed
Reshetnyak Y, Tchedre KT, Nair MP, Pritchard PH, Lacko AG. Structural differences between wild-type and fish eye disease mutant of lecithin:cholesterol acyltransferase. J Biomol Struct Dyn. 2006 Aug;24(1):75-82. PubMed
2004
Linke D, Frank J, Pope MS, Soll J, Ilkavets I, Fromme P, Burstein EA, Reshetnyak YK, Emelyanenko VI. Folding kinetics and structure of OEP16. Biophys J. 2004 Mar;86(3):1479-87. PubMed
Reshetnyak YK, Kitson RP, Lu M, Goldfarb RH. Conformational and enzymatic changes of 20S proteasome of rat natural killer cells induced by mono- and divalent cations. J Struct Biol. 2004 Mar;145(3):263-71. PubMed